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n.3 anno 2002

2002;3(3):125-133 Ricerca originale

Il ruolo della SPECT in associazione a iofupane nella diagnosi della Malattia di Parkinson: i risultati di un’esperienza

Angelo Antonini (1), Giorgio L. Colombo (2)

According to the latest data, in Italy 200.000 patients are affected by the Parkinson™s Disease, and the trend isbound to go up. Generally the diagnosis, crucial in this pathology, is based on the clinic observation. But theabsence of typical signs or symptoms increases the possibility of diagnostic mistakes.
Ioflupane (DATSCAN ® ) is a new diagnostic agent indicated for detecting loss of functional dopaminergicneuron terminals in the striatum of patients with clinically uncertain Parkinsonian Syndromes. The use of Ioflupane (DATSCAN ® ) in association with the single-photon emission computed tomography (SPECT) allowsto improve the diagnosis. Applying systematically this diagnostic model could cause a significant reduction inhospedalization cost, with less trouble for patients and a better quality of life.
Aim of this study is to show the clinical and economic consequences of the use of Ioflupane (DATSCAN ® ) inassociation with SPECT as a new standard for the diagnosis of Parkinson™s Disease, considering theperspective of the National Heath System (NHS) and a single hospital structure.

(1) Centro Parkinson, Dipartimento di Neuroscienze, Istituti Clinici di Perfezionamento, Milano
(2) S.A.V.E - Studi Analisi Valutazioni Economiche, Milano

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